Akademik Veri Yönetim Sistemi
Archives of Gynecology and Obstetrics, cilt.292, sa.1, ss.69-73, 2015 (SCI-Expanded)
Purpose: To investigate serum endocan levels in pregnant subjects with and without pre-eclampsia. Methods: This cross-sectional study was conducted on 49 pregnant women with pre-eclampsia and 32 healthy pregnant women matched for gestational age. Maternal levels of serum endocan were measured with the use of an enzyme-linked immunosorbent assay kit. Results: Mean endocan levels were not significantly different among groups (10.7 ± 4.5 vs. 10.3 ± 3.2 ng/mL, p 0.763). Mean uterine artery PI and RI were higher in the pre-eclampsia group (p < 0.001, p < 0.001). Mean endocan levels were negatively correlated with BMI at the time of blood sampling (r = −0.247, p = 0.044). There was no correlations between mean endocan levels and all the others parameters. Conclusion: These findings suggest that the role of endocan in the pathogenesis of pre-eclampsia was not related to pre-eclampsia; hence, further studies are needed to investigate the role of endocan in the pathogenesis of pre-eclampsia.