Turkiye Klinikleri Cardiovascular Sciences, cilt.23, sa.1, ss.54-60, 2011 (Scopus)
Measurement of resting metabolic rate (RMR) is a necessary component in the evaluation of the diet therapy in obesity. The metabolic rate could be measured by indirect calorimetric methods or estimated by equations. RMR measurements involve the estimation of the oxygen consumption of the individual, which was then converted into units of heat or energy output. In general most investigators involved in RMR measurements use a range of techniques available to estimate oxygen consumption, which provide more or less the same results. Comparisons of techniques using different equipment that there were no significant differences between estimates of oxygen consumption obtained by two or more techniques in the same individual at the same time. Four prediction equations were identified as the most commonly used in clinical practice [Harris-Benedict, Mifflin-St Jeor, Owen, and World Health Organization/Food and Agriculture Organization/United Nations University (WHO/FAO/UNU)]. However, predictive equations might generate errors large enough to impact outcome. The Mifflin-St Jeor equation is more likely than the other equations tested to estimate RMR, but noteworthy errors and limitations exist when it has been applied to individuals and possibly when it has been generalized to certain age and ethnic groups. RMR estimation errors would be eliminated by valid measurement of RMR with indirect calorimetry (ergospirometry, etc.) in obese patients to minimize measurement error and proper planning of diet therapy. In this article, it has been also confirmed that the result of energy restriction on metabolic adaptation is important. Copyright © 2011 by Türkiye Klinikleri.