Turkiye Klinikleri Cardiovascular Sciences, cilt.24, sa.3, ss.231-238, 2012 (Scopus)
Metabolic syndrome is a combination of risk factors for cardiovascular diseases. These metabolic risk factors are hypertension, hyperglycemia, dyslipidemia, prothrombotic factors and proinflammatory factors. Central adiposity and insulin resistance are two components of the metabolic syndrome. Over the years since its first description, it has become clear that the metabolic syndrome encompasses more than just insulin resistance and its associated consequences. Abdominal obesity can be treated with a variety of energy-restricted diets along with regular physical activity. Lifestyle changes in addition to nutritional changes have enormous potential benefits. There is good evidence that a high fiber, low saturated fat diet with increased regular physical activity can reduce the incidence of diabetes for those with impaired fasting glucose tolerance. Cereals, olive and olive oil, red wine, vegetables and fruits, fish, meat (in small amounts), yogurt, cheese, legumes and nuts are main issues of the Mediterranean diet model. Biochemical, clinical and epidemiological research proved that Mediterranean diet has many beneficial effects on health. Of note, subjects who exercise the most, gain the most benefit. Although intensified therapeutic lifestyle changes will help to improve the abnormal lipid profile, some patients may require pharmacotherapy. As conclusion, the fundamental approach in the treatment of metabolic syndrome is reducing weight, increasing physical activity, and changing lifestyle. Copyright © 2012 by Türkiye Klinikleri.